Information on blinding in registered records of clinical trials

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منابع مشابه

Information on blinding in registered records of clinical trials

Information on blinding is part of the data that should be provided upon registration of a trial at a clinical trials registry. Reporting of blinding is often absent or of low quality in published articles of clinical trials. This study researched the presence and quality of information on blinding in registered records of clinical trials and highlights the important role of data-recording form...

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Characteristics of Clinical Trials in Iran: A Sample of 5000 Trials Registered in IRCT

Background and Objectives: A considerable number of clinical trials are conducted in Iran each year. Not much is known about the characteristics of them, this study aimed to investigate key characteristics of Iranian clinical trials.   Methods: All clinical trial protocols registered in IRCT until November 2013 were selected. Text mining techniques were used to extract information from data t...

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Assessing Blinding in Clinical Trials

The interaction between the patient’s expected outcome of an intervention and the inherent effects of that intervention can have extraordinary effects. Thus in clinical trials an effort is made to conceal the nature of the administered intervention from the participants in the trial i.e. to blind it. Yet, in practice perfect blinding is impossible to ensure or even verify. The current standard ...

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Assessment of blinding in clinical trials.

Success of blinding is a fundamental issue in many clinical trials. The validity of a trial may be questioned if this important assumption is violated. Although thousands of ostensibly double-blind trials are conducted annually and investigators acknowledge the importance of blinding, attempts to measure the effectiveness of blinding are rarely discussed. Several published papers proposed ways ...

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Randomisation and blinding in clinical trials

High quality clinical trials are designed to reduce bias, to increase the confidence that the reader can place in the conclusions of the trial. This article evaluates the role of randomisation and blinding to prevent bias and how to best implement them in a trial.

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ژورنال

عنوان ژورنال: Trials

سال: 2012

ISSN: 1745-6215

DOI: 10.1186/1745-6215-13-210